Human Protein Interactions - Exploring Proteasome Interactions

Human Protein Interactions - Exploring Proteasome Interactions

In Large-scale mapping of human protein-protein interactions by mass spectrometry (Ewing et. al. 2007) The authors mapped the interactions of 338 bait proteins in human cells to obtain a data set of 6463 interactions between 2235 distinct proteins. Below is the corresponding power graph, with power edges filtered and centered around Proteasome subunits forming a nice structure between 4 proteasome baits (PSMD10,PSMD13,FLJ11848, and p44S10) and other groups of proteasome subunits. The paper discusses exactly this example in figure 6c.

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