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Sivaraman Subramaniam

Research Interest

Protein-Protein interactions ? Identifying novel interactome involving Red recombineering system in bacteria; Characterization of associated proteins.

Education
1996 ? 1999Bachelor of Science, Biochemistry, University of Madras, India
1999 ? 2000Diploma in Relational Database Management Systems (DRDBMS)
2000 ? 2002Master of Science, Biotechnology, Barkatullah University, Bhopal, India
Research Experience
2002Masters thesis work at Centre for DNA finger printing and Diagnostics (CDFD), Hyderabad, India on ?Development of New Bioinformatics Tools for Restriction Site Engineering and Protein Structure environment analysis?
2002 - 2005Worked as Senior Research Associate at Wockhardt Research Centre, Biotechnology Division, Aurangabad, Maharashtra, India on ?Expression and Characterization of Recombinant human insulin and its analogs from E. coli, H. polymorpha and P. pastoris
2005 ? 2008Doctoral studies at Humboldt University, Berlin, Germany on ?Role of the Cpx pathway in Salmonella pathogenesis?
Publications
Patents:

Sahib Maharaj K; Raju Edupuganti B; Subramaniam Sivaraman; Reddy Vennapusa R; Wockhardt Ltd; ?Purification of insulin-like material by reverse phase chromatography ? Europe EP1758540 ? (2007) United States Published Applications 20080108787 (2008) PCT 2005/115303 ? (2005)

Research Articles:

Subramaniam, S., Müller, V. S., Hering, N. A., Mollenkopf, H., Becker, D., Heroven, A. K., Dersch, P., Pohlmann, A., Tedin, K., Porwollik, S., McClelland, M., Meyer, T. F. and Hunke, S. "Contribution of the Cpx envelope stress system to metabolism and virulence regulation in Salmonella enterica serovar Typhimurium." Molecular Microbiology Submitted on 23.07.11.

Subramaniam, S., Hering, N. A., Mollenkopf, H., Becker, D., Heroven, A. K., Dersch, P., Porwollik, S., McClelland, M., Bumann, D., Meyer, T. F. and Hunke, S. (2009). "The Cpx-envelope stress system of Salmonella typhimurium controls the expression of the intramacrophage type three secretion system regulator SsrB and the twin arginine transporter TatABC."Molecular Microbiology, submitted.

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