Andrea Kranz
Research Topics
Epigenetics, Developmental Genetics and Embryology of the Mouse, Gene targeting, Angiogenesis
CV
| 1994 | Diploma in Biology, Christian-Albrechts-Universität Kiel |
| 1995 | Research fellow, Laboratory of Prof. M. Kendall, Babraham Institute, Cambridge University, United Kingdom |
| 1999 | PhD, "The vascular system as a target for the Vascular Endothelial Growth Factor-A: A mediator for the physiologic and pathologic angiogenesis in human", Laboratory of Prof. J. Waltenberger, Universität Ulm |
| 1999-2000 | Postdoc, Laboratory of Prof. J. Waltenberger, Universität Ulm |
| 2001-2004 | Postdoc, Laboratory of Prof. T.N. Sato, University of Texas, Southwestern Medical Center Dallas |
| 2005 | Postdoc, Laboratory of Prof. T.N. Sato, Weill Medical College, Cornell University New York City |
| 2006-now | Postdoc, Laboratory of Prof. A.F. Stewart, Technische Universität Dresden, BIOTEC |
Scientific Awards
| 1995 | Scholarship of the Dr. Helmut Robert Memorial Foundation |
| 1998 | Ludolf-Krehl-Award of the Southwest-German Society for Internal Medicine |
| 1999 | Gotthard-Schettler-Award of the German Society for Arteriosclerosis-Research |
| 2000 | PhD-Award of the Society of the University Ulm |
Publications
Anastassiadis, K., Glaser, S., Kranz, A., Bernhardt, K. and Stewart, A. F. (2010). "A Practical Summary of Site-Specific Recombination, Conditional Mutagenesis, and Tamoxifen Induction of CreERT2." Methods Enzymol 477C: 109-123.
Kranz, A., Fu, J., Duerschke, K., Weidlich, S., Naumann, R., Stewart, A. F. and Anastassiadis, K. (2010). "An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase." Genesis.
Glaser, S., Lubitz, S., Loveland, K. L., Ohbo, K., Robb, L., Schwenk, F., Seibler, J., Roellig, D., Kranz, A., Anastassiadis, K. and Stewart, A. F. (2009). "The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis." Epigenetics & Chromatin 2: 5.
Hooper, A. T., Butler, J. M., Nolan, D. J., Kranz, A., Iida, K., Kobayashi, M., Kopp, H. G., Shido, K., Petit, I., Yanger, K., James, D., Witte, L., Zhu, Z., Wu, Y., Pytowski, B., Rosenwaks, Z., Mittal, V., Sato, T. N. and Rafii, S. (2009). "Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells." Cell Stem Cell 4: 263-74.
Stadler, N., Eggermann, J., Voo, S., Kranz, A. and Waltenberger, J. (2007). "Smoking-induced monocyte dysfunction is reversed by vitamin C supplementation in vivo." Arterioscler Thromb Vasc Biol 27: 120-6.
Autiero, M., Waltenberger, J., Communi, D., Kranz, A., Moons, L., Lambrechts, D., Kroll, J., Plaisance, S., De Mol, M., Bono, F., Kliche, S., Fellbrich, G., Ballmer-Hofer, K., Maglione, D., Mayr-Beyrle, U., Dewerchin, M., Dombrowski, S., Stanimirovic, D., Van Hummelen, P., Dehio, C., Hicklin, D. J., Persico, G., Herbert, J. M., Shibuya, M., Collen, D., Conway, E. M. and Carmeliet, P. (2003). "Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1." Nat Med 9: 936-43.
von Degenfeld, G., Raake, P., Kupatt, C., Lebherz, C., Hinkel, R., Gildehaus, F. J., Munzing, W., Kranz, A., Waltenberger, J., Simoes, M., Schwaiger, M., Thein, E. and Boekstegers, P. (2003). "Selective pressure-regulated retroinfusion of fibroblast growth factor-2 into the coronary vein enhances regional myocardial blood flow and function in pigs with chronic myocardial ischemia." J Am Coll Cardiol 42: 1120-8.
Kranz, A., Rau, C., Kochs, M. and Waltenberger, J. (2000). "Elevation of vascular endothelial growth factor-A serum levels following acute myocardial infarction. Evidence for its origin and functional significance." J Mol Cell Cardiol 32: 65-72.
Waltenberger, J., Lange, J. and Kranz, A. (2000). "Vascular endothelial growth factor-A-induced chemotaxis of monocytes is attenuated in patients with diabetes mellitus: A potential predictor for the individual capacity to develop collaterals." Circulation 102: 185-90.
Kranz, A., Mattfeldt, T. and Waltenberger, J. (1999). "Molecular mediators of tumor angiogenesis: enhanced expression and activation of vascular endothelial growth factor receptor KDR in primary breast cancer." Int J Cancer 84: 293-8.
Kranz, A., Mayr, U., Frank, H. and Waltenberger, J. (1999). "The coronary endothelium: a target for vascular endothelial growth factor. Human coronary artery endothelial cells express functional receptors for vascular endothelial growth factor in vitro and in vivo." Lab Invest 79: 985-91.
Waltenberger, J., Kranz, A. and Beyer, M. (1999). "Neovascularization in the human heart is associated with expression of VEGF-A and its receptors Flt-1 (VEGFR-1) and KDR (VEGFR-2). Results from cardiomyopexy in ischemic cardiomyopathy." Angiogenesis 3: 345-51.
Head, G. M., Mentlein, R., Kranz, A., Downing, J. E. and Kendall, M. D. (1997). "Modulation of dye-coupling and proliferation in cultured rat thymic epithelium by factors involved in thymulin secretion." J Anat 191 ( Pt 3): 355-65.
Kranz, A., Kendall, M. D. and von Gaudecker, B. (1997). "Studies on rat and human thymus to demonstrate immunoreactivity of calcitonin gene-related peptide, tyrosine hydroxylase and neuropeptide Y." J Anat 191 ( Pt 3): 441-50.
