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Press Releases of the BIOTEC

Here you can find all the press releases of the BIOTEC. If you have questions, don't hesitate to contact Dana Schoder (Dana.Schoder(at)tu-dresden.de) or the press office of the TU Dresden (pressestelle(at)tu-dresden.de).

Do interactions in molecular and cellular networks follow the same organization principles as human social interplay?


22/11/2018

A Researcher from TU Dresden Biotechnology Center found impressing analogies

To decode the underlying laws that govern the organization of life into molecules, cells and tissues are the great scientific challenges of our time. Dr. Carlo Vittorio Cannistraci from the Biotechnology Center (BIOTEC) at the Technical University Dresden, Germany, explored the question whether brain cells interact in the same manner as molecules within a cell and published his findings in the science magazine Nature.

He found that the self-organization within these two systems follows the same principles - regardless the size of the structures and independent from what body functions they support. He codified those complex interactions in a mathematic model that is able to predict protein molecule interactions within the body under changed conditions.


Dr. Carlo Vittorio Cannistraci © BIOTEC

Press release


Biophysicists delve into the organisation of life – New Cluster of Excellence to unravel the “Physics of Life” (PoL)


27/09/2018

To fathom the structure and dynamics of living matter is one of the great scientific challenges of our time. The new Cluster of Excellence "Physics of Life" (PoL) will concentrate on the underlying laws of physics that govern the organisation of life into molecules, cells and tissues. PoL is a collaboration between scientists of TU Dresden and other DRESDEN-concept research institutions such as the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), the Max Planck Institute for the Physics of Complex Systems (MPI-PKS), the Leibniz Institute of Polymer Research (IPF), and the Helmholtz-Zentrum Dresden-Rossendorf.

Stephan Grill, professor of biophysics at TU Dresden's Biotechnology Center (BIOTEC) and spokesperson of the cluster, is thrilled about these developments: "For years, researchers from Dresden have been at the forefront of developing the physics of living matter with the goal of understanding biological processes. We are very proud that our interdisciplinary efforts have now been acknowledged by the Excellence Commission. The time is ripe for physics to tackle its perhaps greatest challenge: to decipher the principles of organisation of living matter. PoL will shed light on tissue formation and structure, while unveiling the mechanisms by which cells organise their inner workings. It is sensible to first understand the controlled formation of organs by cells before attempting to devise ways to inhibit uncontrolled cell growth, e.g. in cancers. Our fundamental research is aimed at understanding life and our approaches will provide solutions to some of the world's most pressing bioengineering and health issues."

Press release

Website of PoL


The team of researchers of the Cluster of Excellence “Physics of Life”, together with TU Dresden’s Rector, Prof. Dr. Müller-Steinhagen (8th from the left). © MPI-CBG


A novel synthetic antibody enables conditional “protein knockdown” in vertebrates


17/08/2018

The research groups led by Dr. Jörg Mansfeld of the Biotechnology Center of the TU Dresden (BIOTEC) and Dr. Caren Norden of the Max Planck Institute for Molecular Cell Biology and Genetics (MPI-CBG) have developed a novel synthetic antibody that paves the way for an improved functional analysis of proteins. They combined auxin-inducible "protein knockdown" with a synthetic antibody to not only observe fluorescent proteins in living cells but also to rapidly remove them in a temporally controlled manner.

Dr. Jörg Mansfeld's research group has developed a novel AID-nanobody in order to not only observe GFP-linked proteins in living cells, but to also rapidly degrade them in a targeted manner for functional analysis. For this purpose, the auxin recognition sequence (AID) was linked to a GFP recognizing antibody that is structurally-related to camelid antibodies (nanobody). It could be shown that this so-called AID-nanobody allows the almost complete degradation of GFP-linked proteins in human cell culture after the addition of auxin. The possibility to follow the degradation of the protein "live" under the microscope makes functional analysis much easier.

Microscopic image of living HeLa cells containing a GFP-linked protein (green) and the AID nanobody (magenta). After addition of the plant hormone auxin, the GFP-linked protein is broken down specifically in the cells containing AID nanobody within 30 minutes. © Jörg Mansfeld

Dr. Jörg Mansfeld © Magdalena Gonciarz

Find here the complete press release


Dr. Ivan Minev receives an ERC Starting Grant of 1.5 million EUR to develop integrated multimodal brain implants


31/07/2018

The European Research Council (ERC) has approved the research project "Integrated Implant Technology for Multimodal Brain Interfaces (IntegraBrain)" with a prestigious and highly competitive Starting Grant of 1.5 million EUR for 5 years. Dr. Ivan Minev, research group leader from the Biotechnology Center of TU Dresden (BIOTEC) and Freigeist-Fellow of the Volkswagen Foundation, wants to establish neuroprosthetic implants for the brain with electrical, chemical, thermal and optical functionalities.

Dr. Ivan Minev's ERC Starting Grant project aims to build devices that enable hearing and speaking with the nervous system in several "languages". The special feature here is that neuronal tissue is treated not only as an electrical but also as a chemical, thermal and optical machine. Dr. Minev and his team aim to combine several sensing and actuation modules in an integrated implantable technology to investigate the combined effects of multimodal neuromodulation.

Vision for an integrated network of sensors and actuators for establishing brain-machine interfaces beyond the electrical functionality. © Ivan Minev


Dr. Ivan Minev © BIOTEC

Find here the complete press release


Sunshine duration might influence the time onset of a deadly type of heart attack


07/05/2018

An international team of scientists led by Dr. Carlo Vittorio Cannistraci, Group Leader of the Biomedical Cybernetics lab at the BIOTEChnology Center (BIOTEC) TU Dresden, has discovered a rule at the basis of the chronobiology of heart attack in humans. The study concludes that seasonal rhythms associated with sun irradiance may influence circadian rhythms of heart attack onset.

Press release

Picture: Sunshine and chronobiology of heart attack across different latitudes (source)


Rapid diagnosis of diseases with novel blood test


01/03/2018

Prof. Dr. Jochen Guck, research group leader at the Biotechnology Center of TU Dresden (BIOTEC), together with medical colleagues from the University Hospital Carl Gustav Carus Dresden and partnering institutes from Dresden (Germany), Cambridge (UK), Glasgow (UK), and Stockholm (Sweden) use a technique called "real-time deformability cytometry" to screen thousands of cells in a drop of blood for unusual appearance and deformability in a matter of minutes. This novel blood test promises to speed up the correct diagnosis of many disease conditions including leukaemia, malaria, bacterial or viral infections, which in turn can lead to a faster and more accurate start of therapy.

Complete press release

Picture: RT-DC in action. The artistic rendering of the microscopic view into the measurement chip shows the trajectories of many individual blood cells flowing from right to left. When encountering sheath flows from top and bottom, they widen to form a "heart" before entering the narrow measurement channel on the left, where the appearance and deformation of the cells are being analysed. ©Daniel Klaue/ZELLMECHANIK DRESDEN GmbH


Second proof of concept grant for Prof. Dr. Jochen Guck


06/02/2018

Prof. Dr. Jochen Guck, research group leader at the Biotechnology Center of TU Dresden (BIOTEC), was awarded a Proof of Concept Grant by the European Research Council (ERC) for the second time. The €150,000 research grant is available for ERC-funded researchers and intended to help exploring the economic potential or innovation potential of EU-funded frontier research. Intellectual property rights are to be established, business opportunities identified or technical reviews of research results carried out.

Press release

Picture: Prof. Dr. Jochen Guck © BIOTEC

 

 


Tracking down pest control strategies: Project to investigate the temperature behavior of the fruit fly "Drosophila" receives research funding of more than 2 million euros


30/01/2018

The German Research Foundation (DFG) has approved the research project "Seasonal temperature acclimation in Drosophila: A multidisciplinary approach" with a funding volume of 2 million euros. The interdisciplinary research team with scientists from seven different research institutions throughout Germany began its work in January 2018.

Press release

Picture: © Friederike Braun/BIOTEC

 

 


The bright side of an infectious protein: Stress sensors promote yeast cell survival


08/01/2018

Prions are self-propagating protein aggregates that can be transmitted between cells. The aggregates are associated with human diseases. Indeed, pathological prions cause mad cow disease and in humans Creutzfeldt-Jakob disease. The aggregation of prion-like proteins is also associated with neurodegeneration as in ALS. The regions within prion-like proteins that are responsible for their aggregation were termed prion-like domains. Despite the important role of prion-like domains in human diseases, a physiological function has remained enigmatic. Researchers at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), the Biotechnology Center of the TU Dresden (BIOTEC, Grill group), and the Washington University in St. Louis, USA have now identified for the first time a benign, albeit biologically relevant function of prion domains as protein specific stress sensors that allow cells to adapt to and survive environmental stresses. Uncovering the physiological function is an essential first step towards closing a gap in understanding the biological role of prion domains and their transformation into a pathological disease-causing state. The discoveries were published in Science.

Picture: Cryo-Electron Microscopy Image of a biomolecular condensate of a Prion Protein.

Contact: Prof. Dr. Stephan Grill

Press release


‘Spying’ on the hidden geometry of complex networks through machine intelligence


08/12/2017

An international team of scientists led by Dr. Carlo Vittorio Cannistraci, Junior Group Leader of the Biomedical Cybernetics lab at the BIOTEChnology Center TU Dresden, has developed 'coalescent embedding': a class of algorithms that leverage machine intelligence to retrieve the hidden geometrical rules that shape the structure of complex networks. From brain connectivity to social media, 'coalescent embedding' can have a future impact on disparate fields dealing with big-network-data including biology, medicine, physics and social science.

Press release

Picture: Machine Intelligence meets complex networks (Source)

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Dresden researchers have pioneered a brain-network bio-inspired algorithm to predict new therapeutic targets of approved drugs


26/09/2017

Press release

 

Picture: Members of Dr. Carlo Vittorio Cannistraci's research group © BIOTEC

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Dresden researchers have developed an intelligent algorithm that automatically identifies significant associations between latent variables in big data sets


13/04/2017

Freigeist Fellowship supports Dr. Ivan Minev in using 3D printing to find ways to repair damage in the human body


05/09/2016

Dr. Jörg Mansfeld receives 1.5 Million EUR ERC Starting Grant to support his cancer research


06/01/2016

Dresden biophysicist receives the 2015 Sackler Prize in Biophysics endowed with US$ 50.000


08/10/2015

Prof. Dr. Stephan Grill honored for excellent research in the field of
mesoscopic physics of cell structure and dynamics

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Photo: © Katrin Boes, MPI-CBG


Sich selbst heilende Axolotl, Organe aus dem 3D-Drucker, ein begehbares Auge und Elegante Würmer unterm Lego-Mikroskop


25/06/2015

Lange Nacht der Wissenschaften: Forschung entdecken und experimentieren

German press release

 

Photo download ©CRTD


Scientists open new chapter in cell biology and medicine


03/02/2015

BIOTEC Junior researcher lays cornerstone for biotech start-up


30/01/2015

BIOTEC Forum 2014


01/12/2014

Molecules, Cells, and Tissue – Biomechanics Across Scales

German Press Release


BIOTEC Researcher is one of the „Highly Cited Researchers 2014”


18/07/2014

European Funding: On the Road to Diagnosis Device for Blood Cells


07/07/2014

BIOTEC Professor transfers research results into commercial application

German Press Release


Axolotl, „CSI BIOTEC“, and Drums Alive – new cells is what the human needs


27/06/2014

HFSP Funding for international Research Project at the BIOTEC: Switching Molecular Engines in Cells with Light


29/04/2014

FANTOM5 - a Parts List for Cell Type Definition


27/03/2014

Creating a three-dimensional Model for the learning Brain


26/03/2014

„Sächsischer Biotechnologietag 2014“ – Converting Basic Research to Commercial Applications


17/03/2014

DFG further funds lipid research in Dresden, Heidelberg und Bonn


22/11/2013

Professorship for Biophysics at the BIOTEC was newly appointed


15/10/2013

Stephan Grill studied molecular, what makes living organisms

See German Press Release.

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Professor Stephan Grill is a new groupleader at the BIOTEC.©BIOTEC


From Basic Research to Therapeutic Application


04/07/2013

Saxony funds five translation projects of the BIOTEC and CRTD.

See German Press Release.


Interior Design for Stem Cells.


24/06/2013

Axolotl, new Neural Stem Cells, and DNA from Bananas


18/06/2013

Long Night of Science: Discover Science and experiment

German Press Release

 

Download QR-CodeDownload photo: Long Night of Science 2012 in the CRTD ©CRTD
                                                                  

 

 


Natural Scientists and Humanists acquire information together


13/06/2013

A real-time view onto the rules of life


18/04/2013

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