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Regulated amino acid metabolism and immunity

IKL External Seminar

Date:21.05.2019, 16:15 - 17:15
Speaker: Prof. Dr. Peter Murray, Immunoregulation, Max Planck Institute of Biochemistry, Martinsried
Location: CRTD, ground floor, auditorium right
Host: Prof. Dr. Triantafyllos Chavakis

Peter Murray is an international leader in immunometabolism and tumor immunology.

Important papers include:

Stress Kinase GCN2 Controls the Proliferative Fitness and Trafficking of Cytotoxic T Cells Independent of Environmental Amino Acid Sensing. Van de Velde LA, Guo XJ, Barbaric L, Smith AM, Oguin TH 3rd, Thomas PG, Murray PJ. Cell Rep. 2016 Nov 22;17(9):2247-2258

T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells. Marigo I, Zilio S, Desantis G, Mlecnik B, Agnellini AHR, Ugel S, Sasso MS, Qualls JE, Kratochvill F, Zanovello P, Molon B, Ries CH, Runza V, Hoves S, Bilocq AM, Bindea G, Mazza EMC, Bicciato S, Galon J, Murray PJ, Bronte V. Cancer Cell. 2016 Sep 12;30(3):377-390

Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy. Kamei A, Gao G, Neale G, Loh LN, Vogel P, Thomas PG, Tuomanen EI, Murray PJ. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6153-E6161

Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways. Haverkamp JM, Smith AM, Weinlich R, Dillon CP, Qualls JE, Neale G, Koss B, Kim Y, Bronte V, Herold MJ, Green DR, Opferman JT, Murray PJ. Immunity. 2014 Dec 18;41(6):947-59.

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