Examplepictures of DNA-Structures


Müller Cell Gliosis as Pathogenic Factor of Retinal Edema and Neurodegeneration

CRTD External Seminar

Date:09.10.2015, 11:00 - 12:00
Speaker: Prof. Andreas Bringmann Department of Ophthalmology and Eye Hospital, Medical Faculty, University of Leipzig
Location: CRTD, Auditorium left
Host: Prof. Michael Brand

About the research of Andreas Bringmann: The topics of the research are the contribution of Müller cell gliosis to the development of retinal edema and neurodegeneration and functional alterations of the retinal pigment epithelium which may contribute to the development of AMD. Previous research involved studies regarding the functional roles of glial potassium and water channels in the normal and diseased retina, the mechanisms of cellular swelling and the receptor-mediated regulation of the Müller and neuronal cell volume, the role of purinergic receptors in the retinal development and under pathological conditions, and the functional roles of cytokines in the retinal pigment epithelium.


(1) Uckermann O, Vargová L, Ulbricht E, Klaus C, Weick M, Rillich K, Wiedemann P, Reichenbach A, Syková E, Bringmann A. Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea-pig retina. J Neurosci 2004;24:10149-10158.

(2) Pannicke T, Iandiev I, Uckermann O, Biedermann B, Kutzera F, Wiedemann P, Wolburg H, Reichenbach A, Bringmann A. A potassium channel-linked mechanism of glial cell swelling in the postischemic retina. Mol Cell Neurosci 2004;26:493-502.

(3) Bringmann A, Pannicke T, Grosche J, Francke M, Wiedemann P, Skatchkov SN, Osborne NN, Reichenbach A. Müller cells in the healthy and diseased retina. Prog Retin Eye Res 2006;25:397-424.

(4) Bringmann A, Iandiev I, Pannicke T, Wurm A, Hollborn M, Wiedemann P, Osborne NN, Reichenbach A. Cellular signaling and factors involved in Müller cell gliosis: neuroprotective and detrimental effects. Prog Retin Eye Res 2009;28:423-451.

(5) Linnertz R, Wurm A, Pannicke T, Krügel K, Hollborn M, Härtig W, Iandiev I, Wiedemann P, Reichenbach A, Bringmann A. Activation of voltage-gated Na+ and Ca2+ channels is required for vesicular release of glutamate from retinal glial cells implicated in cell volume regulation. Neuroscience 2011;188:23-34. doi: 10.1016/j.neuroscience.2011.04.058.

Structural Phage Assisted Continuous Evolution of Proteins - SPACE-P

TU Dresden iGEM presentation

Date:09.10.2015, 16:00 - 17:00
Speaker: Robert Dinger, Marvin Prein, Abhinaya Anandamurugan, Sethuraman Subramanian
Location: CRTD, auditorium

Our project is called SPACE-P (Structural Phage Assisted Continuous Evolution of Proteins) and is part of the Synthetic Biology field. It focuses on accelerating the process of developing protein binding partners, which is required in pharmaceutical research as well as biotechnology and many other fields of science. Thus far, phage display is the most commonly used method for the discovery of protein binding partners. In this method a large library of potential binding partners is created where the strongest candidates are selected for further affinity testing. This process is very time consuming, cost intensive, requires human intervention steps, and is limited to the size of the given library. Our platform will make it possible to start with a single molecule, transform it by mutation and selection pressure to improve the binding affinity towards a target protein. This method is not only easy to implement, utilizing simple organisms and devices, but also significantly faster and cheaper than currently used tools.

If you would like to get more information about the team please visit their website 2015.igem.org/Team:TU_Dresden

BIOTEC Green Seminar 16.10.2015

BIOTEC Green Seminar

Date:16.10.2015, 11:00 - 12:00
Speaker: Prof. Dan Goldman, Georgia Institute of Technology, Complex Rheology and Biomechanics
Location: CRTD, auditorium left
Host: Jörg Mansfeld
Category: Green Seminar

RAC D - Bone and More

Joint CRTD/SKELMET-Symposium

Date:19.10.2015, 16:00 - 18:00
Speaker: Clemens Bergwitz (Yale University),
Michael Muders (Institute of Pathology,
Andrew Browne (Bone lab, MK3, UKD),
Christopher Antos (CRTD),
Prayag Murawala (CRTD)
Location: CRTD, auditorium left
Host: Lorenz Hofbauer
Category: General, Medicine

CRTD External Seminar 23.10.2015

CRTD External Seminar

Date:23.10.2015, 11:00 - 12:00
Speaker: Verdon Taylor, Stem Cell Center of Competence in Research and Clinical Translation, University of Basel, Switzerland
Location: CRTD, auditorium left
Host: Federico Calegari

CRTD External Seminar 06.11.2015

CRTD External Seminar

Date:06.11.2015, 11:00 - 12:00
Speaker: Fiona Doetsch, Biozentrum, University of Basel, Switzerland
Location: CRTD, auditorium left
Host: Caghan Kizil

"Genetics and the Importance of Nomenclature for Research Mice" & "The Functions and Applications of Alzet Osmotic Pumps in Experimental Research"

Charles River Seminar

Date:09.11.2015, 13:00 - 17:00
Speaker: Jutta Davidson,
Charles River
Location: CRTD, Seminar Room 1 & 2
Host: Katrin Spekl
Category: General

CRTD External Seminar 12.11.2015

CRTD External Seminar

Date:12.11.2015, 16:00 - 17:00
Speaker: José-Alain Sahel, Vision Institute, Paris, France
Location: CRTD, auditorium left
Host: Marius Ader

BIOTEC Green Seminar 13.11.2015

BIOTEC Green Seminar

Date:13.11.2015, 11:00 - 12:00
Speaker: Prof. Helmut Schiessel, Universiteit Leiden, Theoretical Physics of Life Processes
Location: CRTD, auditorium left
Host: Jochen Guck
Category: Green Seminar

BIOTEC Green Seminar 11.12.2015

BIOTEC Green Seminar

Date:11.12.2015, 11:00 - 12:00
Speaker: Prof. Moritz Helmstaedter, Max-Planck-Institute for Brain Research, Department of Connectomics
Location: CRTD, auditorium left
Host: Carlo V. Cannistraci
Category: Green Seminar

Pioneers in Science 11.12.2015

Pioneers in Science

Date:11.12.2015, 14:00 - 15:00
Speaker: Prof. Eric Warrant, Lund University, Department of Biology, Sweden
Location: CRTD, auditorium left
Host: Cristina Golfieri


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