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Cavefish Metabolic Evolution and its Implications for Human Health

CMCB Seminar

Datum:17.05.2018, 16:00 - 17:00
Sprecher: Nicolas Rohner, Stowers Institute for Medical Research, Kansas City Missouri
Ort: CRTD auditorium

Selected Publications:

Cavefish as an evolutionary mutant model system for human disease.
Rohner N.
Dev Biol. 2018 Apr 22. pii: S0012-1606(18)30122-2. doi: 10.1016/j.ydbio.2018.04.013. [Epub ahead of print] No abstract available. 
PMID: 29684312 

Insulin resistance in cavefish as an adaptation to a nutrient-limited environment.
Riddle MR, Aspiras AC, Gaudenz K, Peuß R, Sung JY, Martineau B, Peavey M, Box AC, Tabin JA, McGaugh S, Borowsky R, Tabin CJ, Rohner N.
Nature. 2018 Mar 29;555(7698):647-651. doi: 10.1038/nature26136. Epub 2018 Mar 21.
PMID: 29562229

CRISPR mutagenesis confirms the role of oca2 in melanin pigmentation in Astyanax mexicanus.
Klaassen H, Wang Y, Adamski K, Rohner N, Kowalko JE.
Dev Biol. 2018 Mar 16. pii: S0012-1606(18)30098-8. doi: 10.1016/j.ydbio.2018.03.014. [Epub ahead of print]
PMID: 29555241

Cavefish and the basis for eye loss.
Krishnan J, Rohner N.
Philos Trans R Soc Lond B Biol Sci. 2017 Feb 5;372(1713). pii: 20150487. Review.
PMID: 27994128

Melanocortin 4 receptor mutations contribute to the adaptation of cavefish to nutrient-poor conditions.
Aspiras AC, Rohner N, Martineau B, Borowsky RL, Tabin CJ.
Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9668-73. doi: 10.1073/pnas.1510802112. Epub 2015 Jul 13.
PMID: 26170297 

Cryptic variation in morphological evolution: HSP90 as a capacitor for loss of eyes in cavefish.
Rohner N, Jarosz DF, Kowalko JE, Yoshizawa M, Jeffery WR, Borowsky RL, Lindquist S, Tabin CJ.
Science. 2013 Dec 13;342(6164):1372-5. doi: 10.1126/science.1240276.
PMID: 24337296

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